Amazon Web Services (AWS) developers and solution architects now have an exciting opportunity to leverage NVIDIA Dynamo on NVIDIA GPU-powered Amazon EC2 instances, particularly the Amazon EC2 P6, which is accelerated by NVIDIA Blackwell. This significant update also introduces added support for Amazon Simple Storage Service (S3), already integrated with Amazon Elastic Kubernetes Services (EKS) and AWS Elastic Fabric Adapter (EFA). The enhanced capabilities provided by NVIDIA Dynamo enable businesses to achieve greater performance, scalability, and cost-effectiveness when serving large language models (LLMs) at scale.
NVIDIA Dynamo Scales and Serves Generative AI
NVIDIA Dynamo is an open-source inference-serving framework meticulously designed for large-scale distributed environments. This robust framework is compatible with all major inference frameworks including PyTorch, SGLang, TensorRT-LLM, and vLLM, ensuring broad usability across different applications. Some of its advanced optimization features include:
- Disaggregated Serving: This feature separates the prefill and decode inference stages across distinct GPUs to significantly boost throughput.
- LLM-Aware Routing: By intelligently routing requests, this capability maximizes key-value (KV) cache hit rates while minimizing the costs associated with recomputation.
- KV Cache Offloading: It allows KV cache to be offloaded across cost-efficient memory hierarchies, thereby reducing overall inference costs.
These features collectively empower NVIDIA Dynamo not just to serve AI applications but to do so with unmatched efficiency and cost-effectiveness for large-scale, multi-node LLM deployments.
Seamless Integration with AWS Services
For AWS developers and solution architects focusing on LLMs, the greatest benefit of NVIDIA Dynamo lies in its seamless integration into existing AWS cloud architectures:
- Amazon S3: Dynamo NIXL now supports Amazon S3, a highly scalable and cost-effective object storage service. Computing KV cache is resource-intensive; hence, offloading it to S3 can free up precious GPU memory crucial for serving new requests. This means developers can significantly reduce overall inference costs while simplifying their architecture by eliminating the need for custom plugins.
- Amazon EKS: Dynamo operates seamlessly within Amazon EKS, a fully managed Kubernetes service. As LLMs evolve in size and complexity, high-performing inference deployments demand advanced features such as LLM-aware request routing and KV cache offloading. This integration simplifies deployment in EKS-managed Kubernetes clusters, allowing developers to swiftly launch new Dynamo replicas during workload spikes.

- AWS Elastic Fabric Adapter (EFA): Dynamo’s NIXL data transfer library also seamlessly supports Amazon’s EFA. This network interface is designed for low-latency inter-node communication between Amazon EC2 instances. As LLMs increase in complexity and size, sharding them across multiple GPUs becomes essential for enhancing throughput while maintaining low latency. With the backing of EFA, Dynamo enables easy movement of KV cache across nodes with simple commands, thereby streamlining access to its advanced features like disaggregated serving and accelerating the time to production for AI applications.
Optimizing Inference with Dynamo on Blackwell-Powered Amazon P6 Instances
Dynamo isn’t just limited to any NVIDIA GPU-accelerated AWS instance; when combined with Amazon EC2 P6 instances powered by Blackwell, it significantly enhances the performance of advanced models like DeepSeek R1 and the latest Llama 4. Dynamo smooths the often complex process of serving disaggregated Mixture of Experts (MoE) models by managing key tasks like autoscaling for prefill and decode functions.
The Amazon P6-B200 instance introduces groundbreaking features such as fifth-generation Tensor Cores and FP4 acceleration, alongside a twofold increase in NVIDIA NVLink bandwidth compared to previous generations. Furthermore, the P6e-GB200 Ultra Servers utilize a unique scale-up architecture optimized for massive bandwidth, ideal for handling intricate communication patterns in MoE deployments. This potent combination of Dynamo and Blackwell-powered P6 instances leads to superior GPU utilization, higher request throughput for every dollar spent, and sustainable profit margins for AI workloads at scale.
Get Started with NVIDIA Dynamo
The integrations of NVIDIA Dynamo with AWS empower developers to easily scale their inference workloads without the usual complexities. Whether you are venturing into generative AI or optimally deploying LLMs, NVIDIA Dynamo works seamlessly with any NVIDIA GPU-accelerated AWS instance. Dive into the world of optimization and elevate your inference stack by deploying with NVIDIA Dynamo today.
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